{"id":333,"date":"2010-06-07T15:21:04","date_gmt":"2010-06-07T20:21:04","guid":{"rendered":"http:\/\/blogs.montclair.edu\/creativeresearch\/?p=29"},"modified":"2019-02-11T10:13:08","modified_gmt":"2019-02-11T15:13:08","slug":"the-implications-of-weight-gain-in-pregnancy-a-scientists-personal-experience-inspires-her-research-to-help-future-generations","status":"publish","type":"post","link":"https:\/\/www.montclair.edu\/creative-research-center\/2010\/06\/07\/the-implications-of-weight-gain-in-pregnancy-a-scientists-personal-experience-inspires-her-research-to-help-future-generations\/","title":{"rendered":"The Implications of Weight Gain in Pregnancy: A Scientist’s Personal Experience Inspires Her Research to Help Future Generations – by Diana Thomas"},"content":{"rendered":"

CRC Editor\u2019s Note \u2013 On June 5th<\/sup>, the very same day we received Diana Thomas\u2019s essay, I picked up\u00a0The New York Times <\/em>and saw this article on the front page:\u00a0Growing Obesity Increases Perils of Childbearing.<\/a><\/p>\n

*\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0*\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0*<\/p>\n

I had always been athletic and slim if even on the overly skinny side until about 12 years ago.\u00a0\u00a0I wasn\u2019t alarmed when I first started gaining weight, as I was confident that I could easily lose the extra pounds if I needed to.\u00a0\u00a0Unfortunately, I was not aware how much my new sedentary life as a professor and mother would make it difficult to achieve my previous healthy weight.\u00a0\u00a0As it became increasingly more challenging to get in and out of my two-door Honda Civic, I realized it was time for action.\u00a0\u00a0I started my new position as an\u00a0assistant professor at 麻豆传媒在线 in September 2000 and began the hard work of losing almost 70 lbs of excess weight.<\/p>\n

As I started shedding pounds, I began to mathematically investigate the mechanics behind how humans lose and gain weight.\u00a0Pam Delaney (Biochemistry).<\/p>\n

John Stevens (Math), and I collaboratively developed our first model that predicted weight change, which I primarily used for engaging students in the classroom and answering questions about weight change for family and friends.<\/p>\n

Student interest in the topic was high and based on a student project, Baojun Song (Math) and I developed the first model simulating weight change during starvation.\u00a0\u00a0During this time, I lost over 60 lbs of excess weight and just as I stepped back into pre-pregnancy clothes, I discovered I was carrying my second child.<\/p>\n

Desperately concerned about going through a weight loss process again, I carefully monitored my weight gain during pregnancy, ate well, swam at Panzer pool or worked out on the elliptical daily.\u00a0\u00a0Upon reading JF Clapp, M.D.\u2019s\u00a0Exercising through your Pregnancy<\/a><\/p>\n

I began to think about the dynamics of weight change during pregnancy resulting from changes in exercise and diet.\u00a0\u00a0I contacted Dr. Clapp in 2004 and we collaboratively developed a model for fetal growth in utero based on maternal exercise and diet.\u00a0\u00a0The paper, which appeared in Royal Society Publication<\/a> set in motion a series of events that permanently altered the course of my research career.<\/p>\n

Attention from the publication resulted in current collaborations with\u00a0Steven Heymsfied, M.D. and \u00a0Corby Martin, Ph.D.<\/a><\/p>\n

Dr. Heymsfield is an expert in human body composition who has studied weight change from a quantitative point of view for over 30 years. Dr. Heymsfield and I have looked at how body composition is a mathematical function of race, gender, age and height using a large cross-sectional data set representative of the current US population. This function is at the core of all the weight loss models we have developed.<\/p>\n

Dr. Martin is a behavioral psychologist who is investigating adherence to lifestyle changes that promote weight loss at\u00a0Pennington Biomedical Research Center<\/a>.<\/p>\n

Dr. Martin and I collaboratively designed a model we use to monitor patient adherence to diets.\u00a0\u00a0The idea we developed is simple and effective. Applying our validated math model, we generate a weight loss curve for each individual patient based on their prescribed diet. If the patient is non-compliant, their actual weight loss will not follow the trajectory predicted by the model offering an opportunity for immediate interventions by the clinical staff.<\/p>\n

These\u00a0collaborations and others<\/a> and the ongoing questions they have generated, have led me far away from mainstream mathematical research.\u00a0\u00a0Instead of working in an office with pencil and paper, I am now running clinical trials which will provide additional mathematical insight into weight gain and loss in individuals.<\/p>\n

I am currently at the end of my first clinical trial with St. Barnabas Medical Health Center on placental volume and fetal growth during pregnancy.\u00a0\u00a0We have enrolled 12 pregnant women in the study and are investigating how their placenta grows during gestation by conducting a 3-D ultrasound every five weeks of the pregnancy.\u00a0There is a growing body of evidence that placental volume is controlled by maternal diet and exercise.\u00a0\u00a0Placental volume has been also correlated to birth weights and the baby\u2019s percent fat.\u00a0\u00a0Larger infant percent fat mass has been connected to childhood obesity and therefore mathematically correlating these seemingly independent pieces of gestation is highly significant.<\/p>\n

My mathematical background makes me a unique member of my research team which consists of physiologists, nutrition scientists, medical health professionals, and psychologists.\u00a0\u00a0More important, however, is that I am the only individual on our research team that has lost a significant amount of weight and this gives me a personal insight into what challenges our subjects encounter in their\u00a0weight loss efforts.<\/p>\n

As I examine the data, I cheer\u00a0their hard work and hope to simplify and enhance interventions so that they make the most impact possible for individual healthy weight maintenance.<\/p>\n

Diana Thomas, PhD<\/strong>, Associate Professor of Mathematics, 麻豆传媒在线<\/p>\n","protected":false},"excerpt":{"rendered":"

CRC Editor\u2019s Note \u2013 On June 5th, the very same day we received Diana Thomas\u2019s essay, I picked up\u00a0The New York Times and saw this article on the front page:\u00a0Growing Obesity Increases Perils of Childbearing. *\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0*\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0* I had always been athletic and slim if even on the overly skinny side until about 12 years ago.\u00a0\u00a0I […]<\/p>\n","protected":false},"author":23,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-333","post","type-post","status-publish","format-standard","hentry","category-creative-research-center-guest-essay"],"_links":{"self":[{"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/posts\/333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/comments?post=333"}],"version-history":[{"count":5,"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/posts\/333\/revisions"}],"predecessor-version":[{"id":1020,"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/posts\/333\/revisions\/1020"}],"wp:attachment":[{"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/media?parent=333"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/categories?post=333"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.montclair.edu\/creative-research-center\/wp-json\/wp\/v2\/tags?post=333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}