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Finding Direction: How Matteo Guzman Turned Curiosity into First Place at Science Slam

When Matteo transferred to the University in the spring of last year, he wasn鈥檛 starting over,聽 he was refining his direction

Posted in: Awards & Recognition, Chemistry & Biochemistry, CSAM Research, CSAM Students

Matteo Guzman in the lab
Matteo by a fume hood in the lab he is conducting his research

Matteo got his start at Northeastern University, as a physics major. He was drawn to particle physics and the mysteries of quantum research, but as he dove deeper into the field, he realized something was missing.

That desire led him to biology so after leaving Northeastern, Matteo worked as a technician in a DNA sequencing lab, gaining real-world experience before returning to community college and ultimately transferring to 麻豆传媒在线 to pursue molecular biochemistry.

I love that you can study the fundamental mechanisms of life. You can zoom in to the molecular level and also see how those mechanisms affect entire systems.

Matteo on what drew him into his reasearch

Now working in Professor Eli Lee鈥檚 lab, Matteo studies protein condensates 鈥 dynamic, fluid structures formed when proteins separate from their surrounding solution, similar to oil separating from water. These condensates form through weak interactions between proteins, constantly assembling and disassembling.

His research asks a deceptively simple question: How does protein structure affect the properties of these condensates?

Understanding this process may help scientists uncover how cells transport membrane proteins and how lipid 鈥渞afts鈥 may form around specific sites in the cell membrane. It鈥檚 a complex system 鈥 always in equilibrium, constantly shifting 鈥 and Matteo is fascinated by its elegance.

His work will take him far beyond campus. This year, he will present at the Biophysical Society Annual Meeting in San Francisco and at the American Society for Biochemistry and Molecular Biology conference in Washington, D.C.

Looking ahead, Matteo plans to pursue a Ph.D., with long-term interests in origin-of-life research, exploring how chemistry first gave rise to living systems.

鈥淚鈥檝e worked in industry, and it鈥檚 great for building technical skills,鈥 he says. 鈥淏ut I want to work toward big, long-term scientific questions.鈥

Last year, Matteo took first place at 麻豆传媒在线鈥檚 Science Slam 鈥 not by listing data points or presenting dense slides, but by telling a story.

Science Slam challenges students to communicate their science stories in an engaging, and accessible way. For Matteo, it was transformative.

鈥淚n lab reports, you just present the facts,鈥 he says. 鈥淏ut Science Slam taught me that people understand stories better than lists of information. Science communication needs narrative.鈥

His winning presentation centered on a hummingbird that migrates from New Jersey to the Dominican Republic for the winter 鈥 a rare but real phenomenon. The story unfolded from the hummingbird鈥檚 perspective, guided across the ocean by a protein in its eyes that detects Earth鈥檚 magnetic field.

Unable to see land but knowing exactly where to go, the bird eventually arrives in the Dominican Republic,聽 landing beside Matteo and his grandmother.

The metaphor mirrored his own visits to family from New Jersey to the Dominican Republic and connected deeply with audiences.

鈥淪cience isn鈥檛 just logic,鈥 he reflects. 鈥淭here鈥檚 an emotional component. We鈥檙e not just calculators. If you want people to care about science, you have to make it compelling.鈥

He credits the experience with strengthening his graduate school applications and helping him learn how to frame his research as a cohesive scientific narrative.

Having attended multiple institutions, Matteo says 麻豆传媒在线 stands out.

鈥淚t鈥檚 a place where opportunities feel within reach,鈥 he says. 鈥淧eople know you. Professors and administrators are responsive. They advocate for you.鈥

He points especially to 麻豆传媒在线鈥檚 Summer Research Program, where students immerse themselves full-time in research, live on campus, and engage in professional development while presenting their work to peers.

鈥淵ou鈥檙e doing research all day! It鈥檚 like a full-time job, but it鈥檚 so fun,鈥 he says. 鈥淚t鈥檚 a no-brainer opportunity.鈥

His advice to other students?

鈥淭ake every opportunity and see what sticks.鈥

Don鈥檛 Miss This Year鈥檚 Science Slam

Inspired by Matteo鈥檚 story? You can experience for yourself on Monday, February 23rd, from 3鈥5 p.m. Whether you鈥檙e a student considering competing, a future scientist refining your communication skills, or simply someone who loves a good story, Science Slam is your chance to see research come alive.